To start this season's College Football Playoff, the Oregon Ducks (11-1) will host the James Madison Dukes (12-1) starting at 7:30 p.m. ET at Autzen Stadium in Eugene, Oregon. Oregon is favored by 21 points.
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Oregon vs. James Madison Matchup Info
- Game date: Saturday, December 20, 2025
- Game time: 7:30 p.m. ET
- Location: Eugene, Oregon
- Venue: Autzen Stadium
- TV channel: TNT
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Oregon vs. James Madison Odds and Prediction
- Spread favorite: Ducks (-21)
- Moneyline: Ducks (-1923), Dukes (+1010)
- Total: 50.5 points
- Pick ATS: James Madison (+21)
- Pick OU: Over (50.5)
- Prediction: Oregon 33, James Madison 20
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Oregon vs. James Madison Betting Records and Insights
- Oregon has compiled a 7-5-0 ATS record so far this year.
- James Madison has put together an 8-5-0 record against the spread this year.
- When playing as at least 21-point favorites this season, the Ducks have an ATS record of 3-3.
- A total of six out of 12 Oregon games this season have hit the over.
- In 2025, five James Madison games have hit the over.